Diabetic Macular Edema Visual Outcomes Predictable With OCT Biomarkers
Baseline OCT biomarkers may predict visual outcomes in patients with center-involving diabetic macular edema.
Researchers found that certain biomarkers, such as hyperreflective foci (HRF), disrupted ellipsoid zone (EZ)/external limiting membrane (ELM), disorganization of retinal inner layers (DRIL), and hyperreflective choroidal foci (HCF), have the potential to serve as predictors of poorer vision in patients with center-involving diabetic macular edema (CI-DME).
A systematic review and meta-analysis was conducted to evaluate the prognostic significance of baseline structural optical coherence tomography (OCT) biomarkers in patients with CI-DME undergoing anti-vascular endothelial growth factor (VEGF), steroid, or laser therapy.
The study, published in the American Journal of Ophthalmology, assessed the associations between these biomarkers and visual acuity (VA) levels and changes in VA at 6, 12, and 24 months after treatment initiation.
Baseline OCT biomarkers may predict visual outcomes in patients with center-involving diabetic macular edema.
Author's summary: OCT biomarkers predict visual outcomes in diabetic macular edema patients.
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