Rise in Early-Onset Cancer Not Linked to Rise in Clinically Meaningful Cancer Occurrence
A study published in JAMA Internal Medicine found that the increase in early-onset cancer incidence does not consistently indicate an increase in the occurrence of clinically meaningful cancer.
Researchers, including Patel, MD, MPH, from Harvard Medical School in Boston, examined the trend of early-onset cancer and found that while the incidence of 8 specific cancers has doubled since 1992, the aggregate mortality remained flat.
The 8 cancers with the fastest-rising incidence include thyroid, anus, kidney, small intestine, colorectum, endometrium, pancreas, and myeloma. A slight increase in mortality was seen for colorectal and endometrial cancer, while stable or declining mortality alongside increasing diagnoses for the other cancers suggests that the trend is accounted for by increased detection.
The increase in early-onset cancer incidence does not consistently indicate an increase in the occurrence of clinically meaningful cancer.
Author summary: Early-onset cancer rise not linked to clinically meaningful occurrence.
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